We are a GI cancer bioinformatic research Team at the Sun Yat-sen university Cancer Center. We are also part of the bioinformatic platform of SYSUCC leading by Professor REN Jian(For more about RenLab, please go to https://renlab.org/).
Our research goal is development of novel algorithm, application, database tools for GI cancer omic data analysis; Identification of biomarkers for tumor diagnosis and prognosis with machine-learning approaches.
Here are some feild that we currently work on:
Biomarkers for Cancer Immunotherapy
Software and Database related to Cancer genomics
Development novel targeting treatment strategies for GI cancers
Machine Learning based models for cancer diagnosis and prognosis
Gut Microbiota and tumor Microenvirment in Cancer Immunotherapy
Genomic based cancer evolution analysis of Gastric mixed adenoneuroendocrine carcinoma (MANEC) is finally publihsed in Cell Report link22. May. 2023
Our group performed a comprehensive analysis between mutational signatures and tumor microenvironment in pan cancers. The result is published on line at Front. Immunol link1. March . 2023
VSOLassoBag have been published as a cover story in Journal of Genetics and genomics. link24. May . 2022
MPTevol published online in Briefings in bioinformatics! A practical computational framework for comprehensively exploring the Multiple primary tumor(MPT) from multiregion sequencing (MRS) experiments. link29. April . 2022
Our team lead by Prof Xu reported main result of Chankang project: Genomic analysis of 1015 Chinese ColorectalCancer patients reveals a subgroup defined by mitochondrial genomic alterations link15. March . 2022
Our group has published a new review artile related about diagnosis gastric cancer with new Raman Technology By Kunxiang Liu link. Congrat!1. February . 2022
Our new software, CaMutQC by Xin Wang, has been accepted as poster presentation in the coming AACR 2022 conference, Congrat!