Latest News
Our new ecDNA allocation algorithm GCAP is now live! linc. Congratulations to Shixiang Wang! GCAP enables determination of ecDNA status from whole-exome sequencing (WES) datasets. Using GCAP, we further reveal that ecDNA may serve as a promising biomarker for ICI treatment in gastrointestinal (GI) cancers.
“We developed a bioinformatics tool repository for indexing and commenting thousands of tools, which was recently highlighted as a cover story in Science China Life Sciences.” linc
“Our study on the single-cell dynamic microenvironment of EBV-positive gastric cancer before and after anti-PD1 treatment” is now published in Signal Transduction and Targeted Therapy. link
The genomic evolution analysis of gastric mixed adenoneuroendocrine carcinoma (MANEC) is now published in Cell Reports. link
Our comprehensive analysis of mutational signatures and tumor microenvironment across pan-cancers is now online in Frontiers in Immunology. link
MPTevol, a practical computational framework for exploring multiple primary tumors (MPT) from multiregion sequencing (MRS) data, is now online in Briefings in Bioinformatics. link
Led by Prof. Xu, our team reports major results from the “Chankang Project”: genomic analysis of 1015 Chinese colorectal cancer patients reveals a mitochondrial genomic alteration-defined subgroup. link
